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Technology Description

Our Innovation:

-New method for supplying a functional liquid to biosensor micro-chambers in biosensor devices for multiple-analyte analysis.
-The amount of functional liquid supplied to each biosensor micro-chamber can be independently controlled and can flood at least one biosensor micro-chamber in a functional time period at an accurate very low flow rate by using the fluidic circuit.
-The flow of the functional liquid is selectively inlaid in the biosensor microchambers by one or more micro-valves controlled by an injection control unit so that the flow in each biosensor micro-chamber can be independently controlled with great accuracy.
-It is possible to multiplex a functional liquid to a plurality of biosensor micro-chambers accordingly to a pulsating flow mode.
-it is possible to supply within a functional time period each biosensor micro-chamber with an identical amount of functional liquid and the biosensor behaves as in the continuous flow mode with very low flow rate.

Potential Benefits

Competitive advantages: cost-effective device, that provide fast, simultaneous and real-time responses. A great reduction of the total flow of the functional liquid. Sensitive and accurate performance for multiple-analyte analysis that meet clinical requirements.

Limitations

To be determined during further development

Suggested Applications

Patient need addressed: Multi-analyte detection for specific diseases

Case manager

Aida Castellanos Paez

Status
International patent application PCT/EP2018/062230 (May 11, 2018)
Availability
Licensing or Assignment
Inventor(s)
Giacomo Saviozzi, Juan Pablo Salvador, Manuel Lopez de Miguel, Francisco Palacio, Raquel Pruna, Ma. Pilar Marco, Cecilia Laschi

Centro de Investigación Biomédica en Red, Bioingeniería, Biomateriales y Nanomedicina

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The Biomedical Networking Research Center of Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN) is one of the 11 thematic areas of CIBER. CIBER groups some of the main Spanish research groups (more than 400) in biomedicine, located in more than 100 institutions distributed around Spain. Website: http://www.ciber-bbn.es/
The technological areas
Life sciences, Medicine

Technology Readiness Level 3